End-to-end Evidence Development, Optimization and Communication for the Life Sciences Industry.

WHO WE ARE
Genesis Research is an international healthcare consultancy providing end-to-end evidence development, optimization and communication services for Life Sciences groups.
Our Guiding Principles
DATA-DRIVEN
VISUALIZATION
PARTNERSHIP AT HEART
VALUE FOCUSED
THE BIG PICTURE
Services - Evidence Development, Access, and Communication for Life Sciences Groups
-Genesis/Services
RESEARCH
EVIDENCE DEVELOPMENT
Assembling and integrating high-quality scientific evidence is critical to gathering insights on patient outcomes, therapeutic area needs and product value. We offer a suite of services that employs rigorous qualitative and quantitative research methods to effectively generate actionable intelligence.

Our research services include:
  • Real World Data and Advanced Analytics
  • MetaResearch
  • Modeling and Simulation
  • Real World Data Collection
  • Clinical Trial Based Services
OPTIMIZE
EVIDENCE ACCESS
The true potential of your data assets can be unlocked through intuitive, interactive and user-friendly analytic platforms. Our customized and innovative solutions disseminate evidence and demonstrate value efficiently across various stakeholders.

Our optimization services include:
  • Graphical User Interfaces
  • Knowledge Platforms
  • Augmented Deliverables
COMMUNICATE
EVIDENCE COMMUNICATION
We leverage our technical expertise, writing and editorial capabilities to translate complex scientific data into key value messages and evidence. Our team is well-equipped to help you strategize evidence dissemination and create engaging and scientifically valid content to drive decision-making.

Our communication services include:
  • Scientific Writing
  • Content Management
  • Data Visualization
  • Training and Workshops
Research - Generate actionable insights from high quality evidence
Genesis/Services/Research
Real World Data and Advanced Analytics
Real world data is changing the way companies do business and is an essential part of product value.
Genesis applies cutting-edge quantitative and qualitative techniques to generate the best real-world evidence for insight and decision-making.

Our Real World Data and Advanced Analytics research can assist you with a range of analytic services from conceptualization to publication.

Deep expertise with majority of data sources - from databases to registries, together with a continuous open communication and assurance of timelines and quality, guarantee understanding of your research question and finding the appropriate data source that will result in successful engagement.

Our Real World Data and Advanced Analytics services include:
  • Database Analyses
  • Registries and Chart Reviews
  • Data Optimization
  • Pharmacovigilance
  • Epidemiology
  • Biostatistics
MetaResearch
Genesis provides MetaResearch support through rigorous qualitative and quantitative protocols for evidence integration, serving Life Sciences groups across industries - from biopharmaceuticals and medical devices to regulatory and law.
We focus on integrating and strengthening existing scientific evidence as well as identifying and communicating value through simple tools.

We employ powerful evidence synthesis techniques to combine information from disparate sources of clinical and economic data and provide valid and robust outputs.

Our MetaResearch services include:
  • Rapid and Systematic Literature Reviews
  • Meta-Analyses and Network Meta-Analyses
  • Outcomes Synthesis
  • Cost Analyses
  • Epidemiologic Reviews
  • Gap Analyses
  • Burden of Disease Analyses
  • Treatment Pathway Analyses
Modeling & Simulation
Genesis provides full-service modelling support for Life Sciences groups across multiple industries - from biopharmaceuticals and medical devices, to finance and litigation.
Our models provide the highest quality evidence from a quantified representation of systems in cases where direct measurements are not possible.

Our modeling services include:
  • Pharmacoeconomic Models
  • Cost Calculators
  • Forecasting Models
  • Model Review and Validation
  • Model Adaptations
  • Clinical Trial Simulations
  • Disease Simulations
  • Epidemiological Estimates
  • Crossover Adjustments
  • Bayesian Analyses
  • Crossover Adjustments
  • Matching-adjusted Indirect Comparisons (MAIC)
  • Simulated Treatment Comparisons (STC)
  • Multi-Criteria Decision Analyses (MCDA)
  • Model-based Product Development
  • Pharmacogenetic Models
  • Strategic Models and Bespoke Models
Real World Data Collection
Real world data provides unique information on outcomes not studied in clinical trials.
With a team of experienced researchers, programmers, interface developers and analysts, Genesis Research is well positioned to provide Registry services of outstanding quality.

Our Product Registries include all or a subset of patients exposed to a drug, device or biologic. Our expertise ensures successful implementation at every step of the process. From planning and design through selection of data elements and data sources, we provide continuous support while always maintaining the highest ethical standards with respect to data ownership and privacy. We have developed a broad range of data collection procedures and systems available and we put great emphasis on quality assurance.

Our full-service Real World Data Collection support includes:
  • Planning and Design
  • Recruitment
  • Data Collection and Quality Assurance
  • Event Detection
  • Processing and Reporting
  • Analysis and Interpretation
Clinical Trial Based Services
The healthcare product industry presents enormous risks and enormous opportunities.
Whether your product has just begun human testing or is already undergoing late-phase trials, we can help you plan your clinical trials and predict their outcomes. We offer customized solutions to help our clients quickly make informed decisions based on top-quality data.
Planning:
  • Clinical Trial Simulation
  • Disease Simulation
  • Site Identification and Profiling using RWD
  • Epidemiological Estimates
  • Literature Reviews
  • Outcome Identification
  • Decision Analytic Modeling
  • Biostatistics Support
  • Scientific and Technical Writing
  • Microcosting
Implementation:
  • Ad Hoc Analysis
  • Background Analysis
  • Clinical Trial Simulation
  • Crossover Adjustments
  • RWD Comparative Arms
  • Scientific and Technical Writing
Results:
  • RWD Comparative Arms
  • Crossover Adjustments
  • Scientific and Technical Writing
  • Meta-Analyses
  • Matching-Adjusted Indirect Comparisons
  • Simulated Treatment Comparisons
Optimize - Maximize understanding and enhance access to the best supporting evidence
-Genesis/Services/Optimize
Graphical User Interfaces
Information has a value only if it is accessible and understandable. Presenting results well is equally important as deriving them well.
Genesis provides customized graphical user interface solutions for internal and external deliverables.

Our human-computer interaction specialists, visualization experts and graphic designers bring collaborative work to best suit information delivery needs - from model interfaces to knowledge sharing platforms and dynamic reports.
Knowledge Platforms
Genesis develops digital solutions that streamline data dissemination and intelligence gathering.
Over the life cycle of a biopharmaceutical product or medical device, large volumes of information are often compiled from disparate sources across multiple departments. As a result, information management, data dissemination and value development is time consuming and tedious.

Genesis has the capabilities to build customized and compatible applications that can serve as centralized information repositories to help our clients generate meaningful insights. These platforms feature intuitive user interfaces, dynamic functionality and high-quality content that is synthesized and mapped appropriately, hence providing a powerful blueprint for effective product value demonstration.

For a live demonstration of these platforms, please contact us.
Augmented Deliverables
Good results are half the battle - how they are delivered is another story.
Genesis provides an augmented format for the delivery of research results. These enhancements facilitate easy navigation through complex data.

Our augmented deliverables are dynamic, concise, interactive and have increased information transfer levels. We use our research expertise in combination with visual storytelling to provide enhanced clarity and a logical information flow.
Communicate - Disseminate high-impact evidence
-Genesis/Services/Communicate
Content Management
From concept to creation, we partner with you to help define, organize, and refine scientific content to ensure maximum impact.
A successful communication strategy hinges on delivering unified, engaging, and high-quality content that is supported by evidence obtained through multiple channels. Through an in-depth examination of stakeholder information needs and available data resources, we coordinate tactics that help convey strong evidence-based messages at the right time and at the right place.

Our services include:
  • Publication Planning and Submissions
  • Evidence Mapping
  • Value Message Development and Content Optimization
Data Visualization
We transform complex information and convey using simple and interactive formats to uncover powerful insights.
While advances in scientific methods and technology allow for deeper dissection of large volumes of data, processing and interpretation of this information becomes challenging.

We address this challenge by developing visual elements that convey and simplify complex data clearly and intuitively. Our focus is on visual storytelling; throughout the design process, we incorporate elements such as readability, applicability, and data integrity to ensure a high quality deliverable.

Our team applies content and design expertise to create graphic data representations and tools that resonate with specific audiences and increase data retention, hence making impactful communications. Our data visualization outputs include infographics, interactive and dynamic charts and narratives, dashboards, and data maps.
Scientific Writing
Clear, concise, and easy to understand medical and regulatory writing.
Our experienced medical writing team has a successful track-record across a wide range of scientific writing activities.

We provide end-to-end editorial and content support for regulatory and medical submissions as well as scientific communications.
Training & Workshops
Our customized training and educational solutions cover a broad range of topics. We can help your team better understand the scope, impact and interpretation of healthcare research.
We develop custom training programs and products for our clients to help their teams execute complex research and communicate results.

Our services include:
  • Clinical and Scientific Evidence Summaries for MSLs
  • User Menus and Technical Guides for HE Models
  • In-person Workshops and Webinars on Real World Data Analytic Research Methodology
  • Outcomes Research Summary Slide Presentations
Industries
-Genesis/Industries
BIOPHARMACEUTICALS AND
MEDICAL DEVICES
The healthcare product industry presents enormous risks and enormous opportunities. New products face many potential stumbling blocks on their way to market.

Genesis Research can help you gain critical insights about your drug, biologic, or device so you can overcome the obstacles it faces throughout its life cycle.
FINANCE
Both investors and healthcare sector executives need to understand the true value and revenue potential of their products. This requires an in-depth assessment of a host of factors from potential competition to questions of regulatory approval.

We help turn complex scientific data into actionable business information for both industry leaders and stakeholders.
HEALTHCARE LITIGATION
Legal and regulatory matters are a reality in the Life Sciences industry.

Our suite of services can generate the information you need to deal with these issues.

Whether you are seeking to demonstrate the safety of your product to regulators or defend your intellectual property against competitors, we can help you make your case.
BioPharmaceuticals and Medical Devices - Critical insights thoughtout product life cycle.
-Genesis/Industries/Biopharmaceuticals and Medical Devices
Clinical Trial Based Services
Delivering critical information to ensure overall success.
For every dollar spent on researching and developing a new healthcare product, $0.52 will be spent on Phase II and III clinical trials.

With so much at stake, it pays to have the best information when planning and executing a clinical trial. Now, more than ever, success will not necessarily go to those with the most resources at their disposal, but rather to those who can leverage data to their advantage. In the modern life-sciences competitive environment, a good product is not enough. Successful companies need to use robust data to inform critical decisions about their clinical trials.

Our clinical trial services help ensure that your product will stand up to scrutiny from regulators, payers, and physicians. Whether your product has just begun human testing or is already undergoing widespread late-phase trials, our suite of practices can help you both plan your clinical trials and predict their outcomes. We offer customized solutions to quickly help our clients make informed decisions based on top-quality data.
MetaResearch
Genesis provides metaresearch support through rigorous qualitative and quantitative approaches for evidence integration, serving life sciences groups across industries - from biopharmaceuticals and medical devices to regulatory and litigation.
We focus on integrating and strengthening existing scientific evidence as well as identifying and communicating value through simple tools.

In collaboration with academic and field experts, we employ powerful evidence synthesis techniques to combine information from disparate sources of clinical and economic data and provide valid and robust outputs.

Our MetaResearch services include:
  • Rapid and Systematic Literature Reviews
  • Meta-Analyses and Network Meta-Analyses
  • Outcomes Synthesis
  • Cost Analyses
  • Epidemiologic Reviews
  • Gap Analyses
  • Burden of Disease Analyses
  • Treatment Pathway Analyses
Modeling & Simulation
Genesis provides full-service modelling support for BioPharmaceuticals and medical devices.
Our models provide the highest quality evidence from a quantified representation of systems in cases where direct measurements are not possible.

Our modeling services include
  • Pharmacoeconomic models
  • Cost Calculators
  • Forecasting Models
  • Model Review & Validation Model Adaptations
  • Clinical Trial Simulations
  • Disease Simulations
  • Epidemiological Estimates, Crossover Adjustments
  • Bayesian Analyses
  • Crossover Adjustments, Matching-adjusted Indirect Comparisons (MAIC)
  • Simulated Treatment Comparisons (STC)
  • Multi-Criteria Decision Analyses (MCDA)
  • Model-based Product Development
  • Pharmacogenetic Models
  • Strategic Models
  • Bespoke Models
Real World Data and Advanced Analytics
Real World Data is changing the way companies do business and is an essential part of product value.
Genesis applies cutting-edge quantitative and qualitative techniques to generate the best real-world evidence for insight and decision-making.

Our Real World Data and Advanced Analytics research can assist you with a range of analytic services from conceptualization to publication.

Deep expertise with majority of data sources - from databases to registries, together with a continuous open communication and assurance of timelines and quality, guarantee understanding of your research question and finding the appropriate data source that will result in successful engagement.

Our Real World Data and Advanced Analytics services include:
  • Database Analyses
  • Registries and Chart Reviews
  • Data Optimization
  • Pharmacovigilance
  • Epidemiology
  • Biostatistics
Scientific Communications
High-quality scientific communication products for a wide variety of audiences
We leverage our technical expertise, writing and editorial capabilities to translate complex scientific data into key value messages and evidence. Our team is well-equipped to help you strategize evidence dissemination and create engaging and scientifically valid content to drive decision-making.

Our services include:
  • Content Management
  • Scientific Writing
  • Data Visualization
  • Training and Workshops
Product Registries
Product Registries provide unique outcomes information on populations under real-world conditions that are not studied in clinical trials.
With a team of experienced researchers, programmers, interface developers and analysts, Genesis Research is superbly positioned to provide Registry services of outstanding quality.

Our Product Registries may include all or a subset of patients exposed to a drug, device or biologic. Our specific expertise ensures successful implementation at every step of the process. From planning and design through selection of data elements and data sources, we provide continuous support while always maintaining the highest ethical standards with respect to data ownership and privacy. We have a broad range of data collection procedures and systems available and we put great emphasis on quality assurance.
Product Value Assessment - Finding the best way to successful acceptance
-Genesis/Industries/Product Value Assessment
Product Valuation
Leveraging data and experience to uncover true value
Having served large and mid-sized pharmaceutical companies, the Genesis Research team has an in-depth knowledge and understanding of value drivers, established and emerging markets, product profiles, trends, pricing, and competition in the Life Sciences industry.

We work to create a forecast of the future value of your product after the successful completion of key stages in its development. We also provide scenario and sensitivity analyses to calculate the risk-adjusted net present value (rNPV) of your product.
Due Diligence
Genesis Research helps you identify and evaluate relevant success factors when engaging your financial assets.
Our due diligence and data assurance competencies enable you to make decisions with confidence through a comprehensive review of the market conditions, competition, deal breakers, and value drivers of interest.
Clinical Trial Simulations
Gaining early insight with the model-based drug development practice.
The ability to estimate the overall success of a trial is a key asset.

The Genesis Research modeling team provides a birds-eye view of the clinical trial process through data generation and data simulation enabling quantified assumptions, quantitative decision-making, and support with complex decisions.
Approval Assessment
Evaluating the probability of success.
Among the greatest hurdles to success for a product is regulatory approval. Failure to receive prompt approval can mean rollout delays, additional trial costs, and loss of shareholder value.

Genesis helps reduce the uncertainty of regulatory outcomes.

Our team uses its scientific and regulatory expertise to accurately anticipate the outcome of an approval application. Whether it is a new product seeking approval or an existing drug seeking relabeling, we can help you know and shape the outcome of a regulatory approval decision.
Healthcare Litigation Support
-Genesis/Industries/Healthcare Litigation Support
Evidence Portfolio
Synthesizing columns of disparate data to achieve clarity.
Whether it's a safety, regulatory, or intellectual property issue, your case is only as good as your evidence portfolio.

Our dynamic deliverables can help you put your best foot forward. Our team has extensive experience generating persuasive evidence to support your case, get approval or protect your intellectual property.
Real World Data and Advanced Analytics
Real world evidence to support all points of the litigation process.
Genesis Research applies cutting-edge qualitative and quantitative techniques to the real-world challenges in Life Sciences litigation sector to generate and communicate strategic evidence.

Our epidemiology and biostatistics experts utilize analytical tools to assess claims related to biopharmaceuticals and medical devices, and help counsel and address issues of causation assessment, temporality of association, roles of differential diagnoses, commonality, and potential damages.

We achieve this through:
  • Real World Data Analyses
  • Epidemiological Analyses
  • Pharmacovigilance
  • Statistical Support
  • Patient Profiling
  • Heat-map Generation
Modeling & Simulation
Using real-world data to simulate outcomes accurately.
Our Modeling and Simulation team draws on commonly used methodological tools and data sources along with their combined decades of experience in order to analyze litigation issues involving pharmaceutical, biotechnology, and medical device products.

We achieve this through:
  • Predictive Modeling
  • Economic and Safety Modeling
  • Simulations and Forecasting
  • Multi-Criteria Decision Analytics
Damage Assessment
Understanding the impact of events is not always straightforward.
Adverse regulatory decisions, patent challenges, and trial failures can all increase cost, force delays, and negatively affect shareholder value.

Our team can help you anticipate and overcome these pitfalls.

Together we can identify and mitigate vulnerabilities.
team-photos
Steve Arikian
Frank A. Corvino
Marko Zivkovic
Jianyi Lee
Steve Arikian, MD
Managing Director
As Managing Director of Genesis Research, Steve overseas all company activities, and is responsible for developing the vision and strategy for Genesis.

"The ability to balance continuity and change in an evolving industry is closely linked to developing a vision. Vision provides guidance about what to preserve and what to change, and lays out a destination; the destination guides your strategy, and strategy leads to action. It is action that leads to success. However, without a powerful team, these are little more than glorified indulgences. It is the continued incorporation of teamwork into our culture that creates the building blocks for success.

At Genesis, we are bridging the worlds of Epidemiology, Clinical and Outcomes Research, Health Economics, Health Services Research and Real World Data Analytics. Teamwork is the secret that allows our extraordinarily talented people to achieve superlative results in this field, and that is one of the key factors driving this company's success."

- Steve Arikian


Steve has over 25 years of experience in Epidemiology and Outcomes Research, including academic appointments at Columbia University, the University of Kentucky and the University of Toronto, as well as tenure in Big Pharma and Consulting. His interests include design and implementation of large-scale database analyses, economic modeling and MetaResearch. He has designed and implemented research projects in the United States, Canada, Latin America, Europe and Australasia.

A co-founder of the International Society for Pharmacoeconomics and Outcomes Research (ISPOR), Steve is widely published in the peer-reviewed literature, is a referee for numerous professional journals, and has been a frequent speaker at industry and trade group sponsored meetings on topics including Database Analytics, Pharmacoepidemiology, MetaResearch, Formulary Management, Pharmaceutical Pricing, and evaluating Product Value.
Frank A. Corvino, PhD
Managing Partner
Head, Real World Data and Advanced Analytics
Dr. Corvino brings over 11 years of experience in Epidemiology, Outcomes Research, and Database Analytics Research. He has worked to bridge the gap in these fields by developing integrative research methodologies as well as sophisticated model interfaces and software products that integrate real world data sources.

"While Genesis is a research organization composed of scientists and physicians, focused on delivering pivotal research to our clients, we are first and foremost in the People Business. There's nothing that I enjoy more than my daily interactions with those that I support.

Maintaining open and active lines of communication enables us not only to build trust and relationships, but it facilitates a flexible and adaptive approach to research that allows each analysis to reach its full potential."

- Frank A. Corvino


Specializing in epidemiology and biostatistics, Dr. Corvino consistently leverages his knowledge of real world data sources to best fit the clinical and economic outcomes of each particular analysis. His real world data expertise includes chart reviews, registry data, clinical datasets, claims and electronic health records.

Dr. Corvino's current research is primarily in oncology, but his expertise and publications span multiple indications including cardiovascular and metabolism, inflammation, immunology, CNS disorders, rare diseases, and infectious diseases. He has designed and successfully implemented research projects in the United States, Canada and Europe. At Genesis Research, Dr. Corvino has managed and/or directed over 300 research engagements in both the US and international settings, across a wide range of disease areas.
Marko Zivkovic, PhD
Vice President, Healthcare Research
Dr. Zivkovic has over 9 years of experience in Epidemiology and Database Analytics Research. He is fluent in complex programming languages including Python, C++, R, SQL, VBA and SAS, and has performed over 200 Healthcare Database Analyses using Marketscan, Clinformatics, CPRD, OnPoint, IPSOS, GE Centricity, SEER, Medicare- SEER and Pharmetrics databases.

At Genesis Research, Dr. Zivkovic manages a team of analysts and plays a pivotal role in the development of technology systems that support and leverage data analytics. Dr. Zivkovic has a particular interest in the development of predictive models and machine learning to facilitate the patient prioritization and clinical insights critical to healthcare management.

Dr. Zivkovic has led numerous projects including large database analyses, health- economic models, chart review database design, product dossiers, software development, and interface development. His projects include disease areas such as diabetes, oncology, cardiovascular conditions, critical care, osteoarthritis, pain management, gastrointestinal disease, respiratory disease, glaucoma, and vaccines.
Jianyi Lee, PhD
Head of MetaResearch
Dr. Lee leads global MetaResearch engagements related to strategic healthcare evidence development and communications. She supports life sciences groups by addressing a broad range of medical information needs through landscape analyses, comparative effectiveness studies, systematic reviews and the development of product value dossiers and scientific publications. In addition to critically evaluating scientific literature on biopharmaceutical products, she leverages her clinical background and product knowledge to draw innovative insights and evidence-based value communication tools. She also serves as an integral scientific resource and provides inputs on healthcare analytic projects.

Dr. Lee brings 10 years of experience in the life sciences industry. Her expertise lies in research design, research methodology and evidence synthesis. She has authored a variety of scientific publications and created a high-quality scientific content in the cardiovascular, metabolic, CNS, dermatology, inflammation, hematology and oncology therapeutic areas.

Prior to joining Genesis, Dr. Lee was responsible for biomedical research activities focusing on neurodevelopmental and cardiovascular biology. She holds a Doctor of Philosophy in Cell Biology and Bachelor of Science in Biology from the University of Virginia.
GENESIS CAREERS Jobs that matter. People we need.
WHAT WE OFFER
REWARDING ENVIRONMENT
No politics - Strong team spirit
DIVERSE GROUP
We come from across the globe
WHO ARE WE LOOKING FOR
Associate Quantitative Experience in the Life Sciences.
Modeling and Simulations
Associate Quantitative analyses using a wide range of healthcare data.
Data Analytics
Analyst Qualitative and quantitative analytic and communication support
MetaResearch
United States
5 Marine View Plaza
Hoboken, NJ 07030
Phone: +1 888 503 2680
Europe
570 Rayners Lane,
Pinner, Middlesex,
Greater London,
HA5 5HY, UK.
Phone: +44 207 096 0340